UNDERSTANDING GIANT CELL TUMOR OF BONE (OSTEOCLASTOMA)
Introduction Giant Cell Tumor of Bone is a rare but noteworthy entity that primarily manifests in the epiphysis, or ends, of long bones such as the femur, tibia, and radius. Though classified as a benign tumor, its behavior can be locally destructive, necessitating a closer look at its characteristics and management. Understanding the Basics 1. What is Giant Cell Tumor of Bone? Giant Cell Tumor of Bone is a unique blend of cellular components, including giant cells and stromal cells. It typically presents as an expansile mass with a propensity for bone destruction. While it usually does not spread to other parts of the body, its local invasiveness requires prompt attention. 2. Who is at Risk? This tumor predominantly affects individuals between the ages of 20 and 40, with a slight predilection for women. While the exact cause is unknown, studies suggest a potential link to genetic factors, though more research is needed to establish a definitive connection. Clinical P...